Can LSD put you in a coma? This is a question that many people are asking after hearing about the serious effects of an LSD overdose. There have been several cases of people who have had to be hospitalized after taking large doses of LSD. Learn more below.

Report of Eight Patients Overdosing on LSD in 1974

In 1974, a paper was published in the Western Journal of Medicine about 8 patients who took a massive dose of pure LSD tartrate powder. Within 15 minutes of intranasal self-administration (snorting), they experienced the following effects:

  • emesis (vomiting);
  • collapsing;
  • sympathetic overactivity;
  • hyperthermia (overheating);
  • respiratory arrest;
  • coma;
  • mild generalized bleeding;
  • platelet dysfunction.

However, for these side effects to occur, the dose has to be extremely high. The patients did not use a typical form of LSD, but a pure powder, possibly mistaking it for another drug. They received supportive care and recovered.

So can LSD put you in a coma? Possibly, if you take a dose hundreds or thousands of times higher than what is normally used to induce hallucinations (100-200 micrograms).

More Recent Cases of LSD Overdose – Did It Cause a Coma?

There have been two cases in recent years that have raised questions about the effects of LSD. In the first case, a 15-year-old girl took 10 times the normal dose of LSD and had to be hospitalized. However, she wasn’t comatose. The other case was a 46-year-old woman who took 550 times the normal dose of LSD and experienced relief from chronic pain. She didn’t go into a coma either.

See also:  LSD Addiction Treatment Programs and Signs of LSD Abuse

In conclusion, can LSD put you in a coma? In theory, yes, and it has happened in history. But practically, it is extremely unlikely, as long as you know that you’re taking LSD at all. It’s virtually impossible to ingest a life-threatening amount of LSD using blotters. Bad trips don’t result in comas.


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